Who we are?
The Centre for Circulating Tumour Cell Diagnostics & Research has been established at the Ingham Institute for Applied Medical Research in mid 2013. Since then the CCDR obtained high end equipment for the isolation of circulating tumour cells (CTCs). These cells, released by virtually all solid cancers into the blood stream, can be interrogated for important, tumour specific, biomarkers that can help to guide therapy, monitor response to therapy and predict failure to therapy while providing new biomarker information of the cancer to predict better patient management. The CCDR also analyses other cancer specific entities (such as circulating tumour DNA, circulating tumour RNA and circulating tumour proteins) in a similar manner to CTCs.
Currently we are strictly engaged in medial research, not routine diagnostics. Nevertheless, some of our research is accompanying clinical trials or has established assays that help to select patients for tailored clinical trials, thus our research is already leading to patient benefit.
What have we been up to?
Collaboration with Andre Franken
Currently Andre Franken from a German collaborating team in Düsseldorf is visiting the CCDR for an exchange of expertise in the analysis of CTCs. Andre has analysed CTCs from breast cancer patients for molecular changes that appear during therapy and currently helps us to develop a biomarker assay for brain cancer.
Recently Francis Young an extremely enthusiastic medical student has finished his BSc(Med) Honours degree with us and the University of New South Wales. Not surprisingly for his ground breaking work in prostate cancer he was awarded a First Class Honours Degree. He has also already co-authored 2 research publications with our team during his year working in the CCDR and we are currently working on a first author publication form his Honours project.
Business as usual
Currently the CCDR and our collaborators have research projects in the following cancers:
- Breast Cancer
- Prostate Cancer
- Ovarian Cancer
- Brain Cancer
- Lung Cancer
- Colorectal Cancer
- Gastric Cancer
- Pancreatic Cancer