Recent publications

  1. Ding, P.N., Becker, T.M., Bray, V., Chua, W., Ma, Y., Bo, X., Lynch, D., de Souza, P., Roberts T.L., Plasma next generation sequencing and droplet digital PCR-based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated with subsequent-line osimertinib. Thoracic Cancer, 2019, doi: 10.1111/1759-7714.13154. [Epub ahead of print]

  2. Nimir, M., Ma, Y., Jeffreys, S., Opperman, T., Young, F., Khan, T., Ding, P., Chua, W., Balakrishnar, B., Adam Cooper, De Souza. P., Becker, T.M., Detection of AR-V7 in liquid biopsies of castrate resistant prostate cancer patients: a comparison of AR-V7 analysis in circulating tumor cells, circulating tumor RNA and exosmes. Cells, 2019, 8(7). pii: E688. doi: 10.3390/cells8070688

  3. Ding, P.N., Becker, T.M., Bray, V., Chua, W., Ma, Y., Bo, X., Lynch, D., de Souza, P., Roberts T.L., The predictive and prognostic significance of liquid biopsy in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: A prospective study. Lung Cancer, 2019, 134:187-193. doi: 10.1016/j.lungcan.2019.06.021

  4. Brungans D, Lochhead A, Iyer A, Illemann M, Colligan P, Hirst N, Splitt A, Liauw W, Vine KL, Pathmandavel S, Carolan MG, Becker TM, Aghmesheh M, Ranson M. Expression of Cancer Stem Cell Markers is Prognostic in Metastatic Gastroesophageal Adenocarcinoma. Pathology, 2019, 51(5): 474-480.                     doi: 10.1016/j.pathol.2019.03.009

  5. Po J.W., Ma Y., Balakrishnar, B., Brungs, D., Azimi, F., de Souza, P. Becker, T.M. Immunomagnetic isolation of circulating melanoma cells and detection of PD-L1 status. 2019 PLoS ONE 14(2): e0211866. pone.0211866

  6. Ding, P.N., Ma,Y.F., Roberts, T.L., Chua, W., Bray, V.J., Lynch, D., Burke, D., de Souza, P., Becker, T.M. Droplet digital PCR-based detection of EGFR mutations in advanced lung cancer patient liquid biopsies: A comparison of circulating tumor DNA extraction kits. Journal of Molecular Biomarkers and Diagnosis 2018, 9(4) 397; DOI: 10.4172/2155-9929.1000397)

  7. Po, J.W., Roohullah, A., Lynch, D., de Fazio, A., Harrison, M., Harnett, P.R., Kennedy, C., de Souza, P., Becker, T.M. Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin. Journal of Circulating Biomarkers 2018, 7:1849454418782617 DOI: 10.1177/1849454418782617)

  8. Brungs, D. Lynch, D. Luk, AWS. Minaei, E. Ranson, M. Aghmesheh,M.  Vine, KL. Carolan, M. Jaber, M. de Souza, P. Becker TM. Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer. World Journal of Gastroenterology 2018; 24 (7), 810

  9. Pang TC, Xu Z, Pothula S, Becker T, Goldstein D, Pirola RC, et al. Circulating pancreatic stellate (stromal) cells in pancreatic cancer—a fertile area for novel research. Carcinogenesis. 2017;38(6):588-91. doi: 10.1093/carcin/bgx030.

  10. Pang T, Xu Z, Pothula S, Becker T, Goldstein D, Pirola R, et al., editors. Circulating Pancreatic Stellate Cells (Cpscs) and Tumor Cells (Ctcs) in Metastatic Pancreatic Cancer. Pancreas; 2017: lippincott williams & wilkins two commerce sq, 2001 market st, philadelphia, pa 19103 USA.

  11. Pang T, Pothula S, Xu Z, Becker T, Goldstein D, Pirola R, et al., editors. Circulating tumor and stellate cells in pancreatic cancer. journal of gastroenterology and hepatology; 2017: wiley 111 river st, hoboken 07030-5774, NJ USA

  12. Luk AW, Ma Y, Ding PN, Young FP, Chua W, Balakrishnar B, et al. CTC-mRNA (AR-V7) Analysis from Blood Samples—Impact of Blood Collection Tube and Storage Time. International journal of molecular sciences. 2017;18(5):1047. doi: 10.3390/ijms18051047

  13. Ding P, Roberts T, Chua W, Becker T, Descallar J, Yip P, et al. Clinical outcomes in patients with advanced EGFR‐mutated non‐small cell lung cancer in South Western Sydney Local Health District. Internal Medicine Journal. 2017. doi: 10.1111/imj.13555

  14. Brungs D, Chen J, Aghmesheh M, Vine KL, Becker TM, Carolan MG, et al. The urokinase plasminogen activation system in gastroesophageal cancer: A systematic review and meta-analysis. Oncotarget. 2017;8(14):23099. doi: 10.18632/oncotarget.15485

Past publications

  • Po J, Lynch D, de Souza P, Becker T. Importance and detection of epithelial to mesenchymal transition phenotype in CTCs.  Tumor Metastasis: InTechOpen; 2016. DOI: 10.5772/64342

  • Ma Y, Luk A, Young FP, Lynch D, Chua W, Balakrishnar B, et al. Droplet digital PCR based androgen receptor variant 7 (AR-V7) detection from prostate cancer patient blood biopsies. International journal of molecular sciences. 2016;17(8):1264. doi: 10.3390/ijms17081264

  • Chen JYJ, Brungs D, Aghmesheh M, Perrow K, Becker T, Carolan M, et al., editors. Expression of urokinase plasminogen activation system in primary gastro-esophageal adenocarcinoma: a systematic review and meta-analysis. asia-pacific journal of clinical oncology; 2016: wiley-blackwell 111 river st, hoboken 07030-5774, NJ USA.

  • Brungs D, Aghmesheh M, Vine KL, Becker TM, Carolan MG, Ranson M. Gastric cancer stem cells: evidence, potential markers, and clinical implications. Journal of gastroenterology. 2016;51(4):313-26. doi: 10.1007/s00535-015-1125-5

  • Tognela A, Spring KJ, Becker T, Caixeiro NJ, Bray VJ, Yip PY, et al. Predictive and prognostic value of circulating tumor cell detection in lung cancer: a clinician's perspective. Critical reviews in oncology/hematology. 2015;93(2):90-102. doi: 10.1016/j.critrevonc.2014.10.001

  • Soon P, Ma Y, Yarrow S, Segara D, Becker T, De Souza P. The Detection Of Circulating Tumour Cells In Patients With Early Breast Cancer: A Pilot Study. Anz Journal of Surgery. 2015;85:4-5.

  • Ouhtit A, Gupta I, Elmageed ZYA, Becker TM. Abstract A20: Deregulation of cell cycle and apoptotic mechanisms in UVB-irradiated p16-mutant inducible melanoma cell lines. American Association for Cancer Research; 2015.

  • Lim S, Spring K, Chua W, Ng W, Descallar J, Ma Y, et al. Circulating tumor cells in locally advanced rectal cancer treated with neoadjuvant chemoradiation. International Journal of Radiation Oncology• Biology• Physics. 2015;93(3):E522-E3.

  • Lim SH, Becker TM, Chua W, Ng W, de Souza P, Spring KJ. Circulating tumour cells and the epithelial mesenchymal transition in colorectal cancer. Journal of clinical pathology. 2014;67(10):848-53. DOI:10.1136/jclinpath-2014-202499

  • Lim SH, Becker TM, Chua W, Caixeiro NJ, Ng W, Kienzle N, et al. Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancer. Cancer letters. 2014;346(1):24-33. doi: 10.1016/j.canlet.2013.12.019

  • Caixeiro NJ, Kienzle N, Lim SH, Spring KJ, Tognela A, Scott KF, et al. Circulating tumour cells—a bona fide cause of metastatic cancer. Cancer and Metastasis Reviews. 2014;33(2-3):747-56. doi: 10.1007/s10555-014-9502-8

  • Becker TM, Caixeiro NJ, Lim SH, Tognela A, Kienzle N, Scott KF, et al. New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use. International journal of cancer. 2014;134(11):2523-33. doi:10.1002/ijc.28516